Testosterone Enantate 250 mg ml Solution for Injection Ampoules Summary of Product Characteristics SmPC emc

In thrombophilic patients, VTE cases have been reported even under anticoagulation treatment, therefore continuing testosterone treatment after first thrombotic event should be carefully evaluated. In case of treatment continuation, further measures should be taken to minimise the individual VTE risk. Caution should be exercised in patients predisposed to oedema, as treatment with androgens may result in increased sodium retention (see 4.8 Undesirable effects). No formal studies have been performed in patients with hepatic impairment. The use of Testosterone Enantate is contraindicated in men with past or present liver tumours (see 4.3 Contraindications).

• Serum testosterone levels should be measured before start of treatment and occasionally during the treatment at the end of an injection interval. (nuttyscientists.com)
• As with all oily solutions, Testosterone Enantate must be injected strictly intramuscularly and very slowly.
• However, it should be taken into account that physiologically testosterone serum levels are lower with increasing age.
• These reactions may occur during or immediately after the injection and are reversible.

Acute toxicity data show that Testosterone Enantate can be classified as non-toxic following a single intake. Even in the case of an inadvertent administration of a multiple of the dose required for therapy, no acute toxicity risk is expected. No special therapeutic measure apart from termination of therapy with the drug or dose reduction is necessary after overdosage. Limited data do not suggest the need for a dosage adjustment in elderly patients (see 4.4 Special warnings and precautions for use).

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Testosterone Enantate is not indicated for use in children and https://www.nirogranite.co.id/aromatasehemmer-steroide-was-sie-uber-ihre-wirkung/ adolescents (see 4.4 Special warnings and precautions for use).

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As with all oily solutions, Testosterone Enantate must be injected strictly intramuscularly and very slowly. Pulmonary microembolism of oily solutions can lead to signs and symptoms such as cough, dyspnoea and chest pain. There may be other signs and symptoms including vasovagal reactions such as malaise, hyperhydrosis, dizziness, paraesthesia, or syncope. These reactions may occur during or immediately after the injection and are reversible. Serum testosterone levels should be measured before start of treatment and occasionally during the treatment at the end of an injection interval.

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In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products. • Peak serum testosterone levels of 1233 ± 484 ng/ml were achieved at 24 hours. Testosterone Enantate replacement therapy may reversibly reduce spermatogenesis (see 4.8 Undesirable effects and 5.3 Preclinical safety data). Testosterone Enantate should not be used in women since, depending on the individual sensitivity to androgenic impulses, women may develop signs of virilisation, e.g. acne, hirsutism, voice changes. To stimulate development of underdeveloped androgen-dependent organs and for initial treatment of deficiency symptoms, 250mg Testosterone Enantate intramuscularly every two to three weeks.